Treatment Tuber cinereum hamartoma
surgical approach removal transsphenoidal @ base of skull.
hormonal suppressive therapy luteinizing hormone receptor agonists leuprolide can used treat seizure component, , effective in patients.
surgery offered if there failure of medical therapy or rapid growth of lesion, specific options including stereotactic thermocoagulation, gamma knife radiosurgery, , physical resection transsphenoidal microsurgery. surgical response typically better when seizure focus has been found eeg originate in or near mass. specific location of lesion relative pituitary , infundibulum , amount of hormonal disturbance @ presentation can predict risk of hypopituitarism following surgery.
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