Technology Platforms for Scalability Integrated nanoliter system

1 technology platforms scalability

1.1 electrokinetic manipulation
1.2 vesicle encapsulation
1.3 mechanical valving

technology platforms scalability

there 3 different technology platforms integrated nanoliter system s scalability. therefore, main processing method of integrated nanoliter system varies type of technology platform using. 3 technology platforms scalability electrokinetic manipulation, vesicle encapsulation, , mechanical valving.

electrokinetic manipulation

the main processing method controlling fluid under technology platform capillary electrophoresis, electrokinetic phenomena. capillary electrophoresis great method controlling fluids because charged particles of fluid being directed controllable electric field within system. however, disadvantage of technique method of controlling fluid s particles heavily depends on particles original charges. disadvantage possible fluid leaks within system. these leaks occur through diffusion dependent on size of fluid s particles.

vesicle encapsulation

the main processing method controlling fluid under technology platform confine fluids of interest in carrier molecules, droplets of water, vesicles, or micelles. carrier molecules (with fluid within them) controlled individually directing each carrier molecules within microfabricated fluidic channels. method great solving possible fluid leaks , since confinement of fluid in carrier molecule not depend on size of fluid s particles. however, technique has disadvantage on how complex solution can when using system.

mechanical valving

the main processing method controlling fluid under technology platform use of small mechanical valves. mechanical valving similar complex plumbing system because microfabricated fluidic channels act plumbing pipes while various controllable valves direct fluid. mechanical valving considered robust solution disadvantages of electrokinetic manipulation , vesicle encapsulation, since mechanical valves operate independent fluid s physical , chemical properties. because physical properties make microfabricated fluidic channels , mechanical valves difficult process due system s extremely small scale, technique has disadvantage of creating integrated nanoliter system mechanical valving nanoliter scale.